Tropical Spastic Paraparesis/Human T Leukemia Virus Type 1--Associated Myelopathy in HIV Type 1--Coinfected Patients | Zendy

Mark A. Beilke | Zendy; S. Japa | Zendy; C. Moeller-Hadi | Zendy; Sheryl MartinSchild | Zendy

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Tropical Spastic Paraparesis/Human T Leukemia Virus Type 1--Associated Myelopathy in HIV Type 1--Coinfected Patients

Author(s) -

Mark A. Beilke,

S. Japa,

C. Moeller-Hadi,

Sheryl MartinSchild

Publication year - 2005

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/432890

Subject(s) - tropical spastic paraparesis , myelopathy , medicine , coinfection , human t lymphotropic virus , leukemia , virology , human t lymphotropic virus 1 , virus , immunology , t cell leukemia , spinal cord , psychiatry

Tropical spastic paraparesis/human T leukemia virus type 1 (HTLV-1)-associated myelopathy (TSP/HAM) is rarely reported in the United States. The causative agents of TSP/HAM are HTLV-1 and, possibly, its cosmopolitan variant, human T leukemia virus type 2 (HTLV-2). Among HTLV-1- or HTLV-2-monoinfected individuals, the estimated lifetime risk for development of TSP/HAM is <2%. However, it has been suggested that HIV/HTLV coinfection may increase the risk for development of TSP/HAM.

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