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Diagnostic Evaluation for Creutzfeldt-Jakob Disease in Massachusetts, 1991-2001
Author(s) -
Manuel López Jara,
Betsey John,
Silvia Kreindel,
Elizabeth WilkRivard,
Alfred DeMaria
Publication year - 2005
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/432723
Subject(s) - medicine , disease , creutzfeldt jakob syndrome , virology , pathology , prion protein
Surveillance for Creutzfeldt-Jakob disease (CJD) in the United States has become a focus of public health attention due to concerns about disease acquired through exposure to transmissible spongiform encephalopathy in other species. A definitive diagnosis requires neuropathologic examination, yet concerns about the invasiveness of procedures and infection control may be barriers to brain biopsy or autopsy in patients with suspected CJD.

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