Enterohemorrhagic Escherichia coli in Human Infection: In Vivo Evolution of a Bacterial Pathogen | Zendy

Alexander Mellmann | Zendy; Martina Bielaszewska | Zendy; Lothar Bernd Zimmerhackl | Zendy; Richard W. Prager | Zendy; Dag Harmsen | Zendy; H. Tschäpe | Zendy; Helge Karch | Zendy

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Enterohemorrhagic Escherichia coli in Human Infection: In Vivo Evolution of a Bacterial Pathogen

Author(s) -

Alexander Mellmann,

Martina Bielaszewska,

Lothar Bernd Zimmerhackl,

Richard W. Prager,

Dag Harmsen,

H. Tschäpe,

Helge Karch

Publication year - 2005

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/432722

Subject(s) - intimin , shiga toxin , escherichia coli , microbiology and biotechnology , pathogen , virology , human pathogen , shiga like toxin , medicine , enterobacteriaceae , gene , biology , genetics

Enterohemorrhagic Escherichia coli (EHEC) cause most cases of the hemolytic uremic syndrome (HUS) worldwide. To investigate genetic changes in EHEC during the course of human infection, we analyzed consecutive stool samples and shed isolates from patients with HUS, focusing on the genes encoding Shiga toxin (stx) and intimin (eae).

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