Modulation of Vaccine‐Induced Immune Responses to Hepatitis C Virus in Rhesus Macaques by Altering Priming before Adenovirus Boosting | Zendy

Christine S. Rollier | Zendy; Ernst J. Verschoor | Zendy; Gláucia ParanhosBaccalà | Zendy; Joost Drexhage | Zendy; Babs E. Verstrepen | Zendy; JeanLuc Berland | Zendy; Nourredine Himoudi | Zendy; Christina Barnfield | Zendy; Peter Liljeström | Zendy; Juan José Lasarte | Zendy; Juan Ruiz | Zendy; Geneviève Inchauspé | Zendy; Jonathan L. Heeney | Zendy

Open Access

Modulation of Vaccine‐Induced Immune Responses to Hepatitis C Virus in Rhesus Macaques by Altering Priming before Adenovirus Boosting

Author(s) -

Christine S. Rollier,

Ernst J. Verschoor,

Gláucia ParanhosBaccalà,

Joost Drexhage,

Babs E. Verstrepen,

JeanLuc Berland,

Nourredine Himoudi,

Christina Barnfield,

Peter Liljeström,

Juan José Lasarte,

Juan Ruiz,

Geneviève Inchauspé,

Jonathan L. Heeney

Publication year - 2005

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/432517

Subject(s) - virology , priming (agriculture) , immunology , semliki forest virus , immune system , biology , dna vaccination , antigen , cd8 , t cell , virus , immunization , biochemistry , botany , rna , germination , gene

Preventive and therapeutic vaccine strategies aimed at controlling hepatitis C virus (HCV) infection should mimic the immune responses observed in patients who control or clear HCV, specifically T helper (Th) type 1 and CD8+ cell responses to multiple antigens, including nonstructural protein (NS) 3. Given the experience with human immunodeficiency virus, the best candidates for this are based on DNA prime, pox, or adenovirus boost regimens.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research