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The host's first line of defense against bloodstream infection with Candida albicans involves the recognition and clearance of the fungus by neutrophils and monocytes/macrophages. The purpose of the present study was to examine changes in the monocytic cell gene-expression profile in response to C. albicans stimulation.

Coculture of THP‐1 Human Mononuclear Cells withCandida albicansResults in Pronounced Changes in Host Gene Expression