Evidence That Interferon‐γ Plays a Protective Role during Cerebral Malaria | Zendy

Sandrine Cabantous | Zendy; Belco Poudiougou | Zendy; Abdoulaye Traoré | Zendy; Marouf M. Keita | Zendy; Mamadou Balla Cisse | Zendy; Ogobara K. Doumbo | Zendy; Alain J. Dessein | Zendy; Sandrine Marquet | Zendy

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Evidence That Interferon‐γ Plays a Protective Role during Cerebral Malaria

Author(s) -

Sandrine Cabantous,

Belco Poudiougou,

Abdoulaye Traoré,

Marouf M. Keita,

Mamadou Balla Cisse,

Ogobara K. Doumbo,

Alain J. Dessein,

Sandrine Marquet

Publication year - 2005

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/432484

Subject(s) - cerebral malaria , parasitemia , malaria , inflammation , immunology , cytokine , interferon gamma , interferon , medicine , microcirculation , plasmodium falciparum

The pathogenic mechanisms of cerebral malaria (CM) are unclear but are thought to involve cytokine-mediated inflammation enhanced by parasite sequestration in the brain microcirculation. The role that interferon (IFN)-gamma could play that would enhance inflammation but also reduce parasitemia is unclear.

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