Open AccessDevelopment of Herpes Simplex Virus Disease in Patients Who Are Receiving Cidofovir
Author(s) -
David Wyles,
Amita Patel,
Nancy Madinger,
Mary Bessesen,
Philip R. Krause,
Adriana Weinberg
Publication year - 2005
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/432477
Subject(s) - cidofovir , virology , herpes simplex virus , virus , biology , medicine
Cidofovir is a nucleotide analogue with antiviral activity against a wide range of DNA viruses, including herpes simplex virus (HSV). In vitro resistance to cidofovir has been reported with use of laboratory HSV strains; clinical failure of cidofovir therapy for HSV disease has also been reported with an isolate that was susceptible by in vitro testing.
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