Discontinuation of Primary Prophylaxis against Mycobacterium avium Complex Infection in HIV-Infected Persons Receiving Antiretroviral Therapy: Observations from a Large National Cohort in the United States, 1992-2002 | Zendy

John T. Brooks | Zendy; Ruiguang Song | Zendy; Debra L. Hanson | Zendy; M. Wolfe | Zendy; David L. Swerdlow | Zendy

Open Access

Discontinuation of Primary Prophylaxis against Mycobacterium avium Complex Infection in HIV-Infected Persons Receiving Antiretroviral Therapy: Observations from a Large National Cohort in the United States, 1992-2002

Author(s) -

John T. Brooks,

Ruiguang Song,

Debra L. Hanson,

M. Wolfe,

David L. Swerdlow

Publication year - 2005

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/432057

Subject(s) - medicine , discontinuation , cohort , mycobacterium avium complex , sida , human immunodeficiency virus (hiv) , public health , cohort study , immunology , viral disease , intensive care medicine , pediatrics , virology , pathology

In a large, diverse cohort of human immunodeficiency virus (HIV)-infected persons receiving routine care, the proportion of eligible persons who discontinued primary prophylaxis against Mycobacterium avium complex (MAC) infection, according to guidelines of the US Public Health Service and the Infectious Diseases Society of America, increased from 16.7% (in 1996) to 84.9% (in 2002). The discontinuation of primary prophylaxis was not associated with an increased risk of disseminated MAC infection.

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