Dengue Virus (DV) Enhancing Antibody Activity in Preillness Plasma Does Not Predict Subsequent Disease Severity or Viremia in Secondary DV Infection | Zendy

Kamolwish Laoprasopwattana | Zendy; Daniel H. Libraty | Zendy; Timothy P. Endy | Zendy; Ananda Nisalak | Zendy; Supamit Chunsuttiwat | Zendy; David W. Vaughn | Zendy; George Reed | Zendy; Francis A. Ennis | Zendy; Alan L. Rothman | Zendy; Sharone Green | Zendy

Open Access

Dengue Virus (DV) Enhancing Antibody Activity in Preillness Plasma Does Not Predict Subsequent Disease Severity or Viremia in Secondary DV Infection

Author(s) -

Kamolwish Laoprasopwattana,

Daniel H. Libraty,

Timothy P. Endy,

Ananda Nisalak,

Supamit Chunsuttiwat,

David W. Vaughn,

George Reed,

Francis A. Ennis,

Alan L. Rothman,

Sharone Green

Publication year - 2005

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/431520

Subject(s) - viremia , dengue virus , dengue fever , antibody , neutralizing antibody , titer , immunology , virology , virus , pathogenesis , viral load , antibody titer , medicine , biology

Dengue hemorrhagic fever, the most severe form of dengue illness, is associated with secondary dengue virus (DV) infection. Preexisting nonneutralizing antibodies to DV that enhance the infection of Fc gamma receptor-bearing cells have been implicated in DV pathogenesis.

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