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Early Levels of HIV‐1 DNA in Peripheral Blood Mononuclear Cells Are Predictive of Disease Progression Independently of HIV‐1 RNA Levels and CD4+T Cell Counts
Author(s) -
Christine Rouzioux,
JeanBaptiste Hubert,
Marianne Burgard,
Christiane Deveau,
Cécile Goujard,
Marc Bary,
D. Séréni,
JeanPaul Viard,
JeanFrançois Delfraissy,
Laurence Meyer
Publication year - 2005
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/430610
Subject(s) - peripheral blood mononuclear cell , rna , immunology , human immunodeficiency virus (hiv) , disease , virology , dna , cell , lentivirus , peripheral blood , peripheral , biology , medicine , immunopathology , viral disease , in vitro , gene , genetics
The objective of this work was to assess the role of human immunodeficiency virus (HIV) reservoirs in the risk of disease progression, by studying the relationship between HIV DNA level in peripheral blood mononuclear cells (PBMCs) and progression toward acquired immunodeficiency syndrome (AIDS).

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