Acute Plasmodium falciparum Malaria Following Splenectomy for Suspected Lymphoma in 2 Patients | Zendy

F. Bidegain | Zendy; Antoine Berry | Zendy; Muriel Alvarez | Zendy; O. Verhille | Zendy; Françoise Huguet | Zendy; Pierre Brousset | Zendy; J Pris | Zendy; B. Marchou | Zendy; JeanFrançois Magnaval | Zendy

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Acute Plasmodium falciparum Malaria Following Splenectomy for Suspected Lymphoma in 2 Patients

Author(s) -

F. Bidegain,

Antoine Berry,

Muriel Alvarez,

O. Verhille,

Françoise Huguet,

Pierre Brousset,

J Pris,

B. Marchou,

JeanFrançois Magnaval

Publication year - 2005

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/430061

Subject(s) - medicine , splenectomy , malaria , lymphoma , malignant lymphoma , plasmodium falciparum , immunology , lymphoproliferative disorders , spleen

Two black African immigrants, with no history of recent travel outside France, received a diagnosis of a malignant lymphoproliferative disorder and splenomegaly, and they subsequently underwent splenectomy. A few weeks after surgery, both patients experienced an acute episode of Plasmodium falciparum malaria, so the initial diagnosis was corrected retrospectively and changed to hyperreactive malarial splenomegaly. These cases illustrate the difficulty in distinguishing hyperreactive malarial splenomegaly from malignant lymphoproliferative disorders and therefore underline the role of the spleen in the immune system's defense against malaria.

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