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Management of Nonsevere Pneumonia in Military Trainees with the Urinary Antigen Test for Streptococcus pneumoniae: An Innovative Approach to Targeted Therapy
Author(s) -
Guchev Ia,
Victor L. Yu,
A. I. Sinopalnikov,
О И Клочков,
Roman S. Kozlov,
L. Stratchounski
Publication year - 2005
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/429919
Subject(s) - medicine , pneumonia , amoxicillin , mycoplasma pneumoniae , clarithromycin , streptococcus pneumoniae , urinary system , chlamydia , community acquired pneumonia , antibiotics , immunology , microbiology and biotechnology , helicobacter pylori , biology
The drug of choice for treatment of Streptococcus pneumoniae infection is generally a penicillin (including amoxicillin). Targeted therapy is, however, rarely used, because results of definitive diagnostic tests for pneumonia are not available for several days. Thus, broad-spectrum antibiotics are used for empirical treatment of pneumonia to cover both typical and atypical pathogens. Our purpose was to assess the usefulness of a strategy of targeted antimicrobial therapy based on the results of a rapid urinary antigen test for S. pneumoniae.

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