Quantification of Adenovirus in the Lower Respiratory Tract of Patients without Clinical Adenovirus-Related Respiratory Disease | Zendy

Anskar Y.H. Leung | Zendy; Mcw Chan | Zendy; Vincent ChiChung Cheng | Zendy; KwokYung Yuen | Zendy; YokLam Kwong | Zendy

Open Access

Quantification of Adenovirus in the Lower Respiratory Tract of Patients without Clinical Adenovirus-Related Respiratory Disease

Author(s) -

Anskar Y.H. Leung,

Mcw Chan,

Vincent ChiChung Cheng,

KwokYung Yuen,

YokLam Kwong

Publication year - 2005

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/429627

Subject(s) - medicine , bronchoalveolar lavage , mastadenovirus , adenovirus infection , adenoviridae , respiratory system , respiratory disease , respiratory tract , respiratory tract infections , immunology , gastroenterology , virology , virus , lung , biology , genetic enhancement , gene , biochemistry

Adenovirus in bronchoalveolar lavage fluid samples from 50 patients without adenovirus-related illness was quantified. In 49 patients, adenovirus was found (median load, 3.3 x 10(3) copies/microg of DNA). The adenovirus load was inversely related to lymphocyte count (Pearson correlation coefficient r = -0.311; P = .03) and was significantly greater in immunosuppressed patients than in immunocompetent patients (5.1 x 10(3) vs. 2.0 x 10(3) copies/microg of DNA; P = .028).

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