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Challenges in the Study of Patients with HIV Type 1 Seroconversion
Author(s) -
Elizabeth Connick,
Samantha MaWhinney,
Cara C. Wilson,
Thomas Campbell
Publication year - 2005
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/429339
Subject(s) - medicine , seroconversion , human immunodeficiency virus (hiv) , virology , immunology , family medicine , medline , political science , law
within 1 and 2 years after infection, respectively, and was observed in ~7% of these persons at 5 years after infection. Low-level viremia is recognized to be correlated with long-term nonprogressive HIV infection [2]. Thus, it is an important clinical end point for studies of interventions during acute-phase and early-phase HIV infection. Nevertheless, use of lowlevel viremia to interpret the impact of treatments in nonrandomized studies of

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