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Modeling the Influence ofAPOC3, APOE,andTNFPolymorphisms on the Risk of Antiretroviral Therapy–Associated Lipid Disorders
Author(s) -
Philip Tarr,
Patrick Taffé,
Gabriela Bleiber,
Hansjakob Furrer,
Margalida Rotger,
Raquel Martínez,
Bernard Hirschel,
Manuel Battegay,
Rainer Weber,
Pietro Vernazza,
Enos Bernasconi,
Roger Darioli,
Martin Rickenbach,
Bruno Ledergerber,
Amalio Telenti
Publication year - 2005
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/429295
Subject(s) - hypertriglyceridemia , lipoatrophy , lipodystrophy , triglyceride , apolipoprotein e , medicine , dyslipidemia , endocrinology , hyperlipidemia , ritonavir , genotype , lipid profile , cholesterol , biology , genetics , viral load , antiretroviral therapy , immunology , diabetes mellitus , human immunodeficiency virus (hiv) , obesity , disease , gene
Single-nucleotide polymorphisms in genes involved in lipoprotein and adipocyte metabolism may explain why dyslipidemia and lipoatrophy occur in some but not all antiretroviral therapy (ART)-treated individuals.

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