Adenovirus Infection after Pediatric Bone Marrow Transplantation: Is Treatment Always Necessary? | Zendy

Tony Walls | Zendy; K. Hawrami | Zendy; Ines UshiroLumb | Zendy; Delane Shingadia | Zendy; Vaskar Saha | Zendy; Ananth Shankar | Zendy

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Adenovirus Infection after Pediatric Bone Marrow Transplantation: Is Treatment Always Necessary?

Author(s) -

Tony Walls,

K. Hawrami,

Ines UshiroLumb,

Delane Shingadia,

Vaskar Saha,

Ananth Shankar

Publication year - 2005

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/429235

Subject(s) - medicine , bone marrow transplantation , adenovirus infection , bone transplantation , transplantation , bone marrow transplant , bone marrow , immunology , virology , intensive care medicine , surgery , virus

Adenovirus infections are associated with significant rates of morbidity and mortality among children after bone marrow transplantation (BMT). Many transplantation units use molecular virological methods, such as polymerase chain reaction (PCR), for surveillance for adenovirus infection and give preemptive antiviral therapy to children with evidence of disseminated adenovirus infection. This treatment strategy has never been evaluated in clinical trials.

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