Prevalence of the ermB Gene in Clostridium difficile Strains Isolated at a University Teaching Hospital from 1987 through 1998 | Zendy

Yajarayma Tang-Feldman | Zendy; Jeffrey P. Henderson | Zendy; G Ackermann | Zendy; Sandor Feldman | Zendy; M. Bedley | Zendy; Joseph Silva | Zendy; Stuart H. Cohen | Zendy

Open Access

Prevalence of the ermB Gene in Clostridium difficile Strains Isolated at a University Teaching Hospital from 1987 through 1998

Author(s) -

Yajarayma Tang-Feldman,

Jeffrey P. Henderson,

G Ackermann,

Sandor Feldman,

M. Bedley,

Joseph Silva,

Stuart H. Cohen

Publication year - 2005

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/428835

Subject(s) - erythromycin , clostridium difficile , microbiology and biotechnology , clostridium difficile toxin a , diarrhea , medicine , gene , clostridium difficile toxin b , clostridiaceae , ribosomal rna , toxin , clostridium , virology , biology , bacteria , antibiotics , genetics

We analyzed 226 strains of Clostridium difficile for the presence of erythromycin ribosomal methylase B (ermB) genes. Forty-four strains (19.4%) carried ermB genes and were resistant to erythromycin. Toxin A and toxin B gene sequences were identified in 81.9% of these 44 strains. Strains of C. difficile that carry ermB genes are common etiologic agents of C. difficile-associated diarrhea.

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