The Role of Immune Reconstitution Inflammatory Syndrome in AIDS‐RelatedCryptococcus neoformansDisease in the Era of Highly Active Antiretroviral Therapy | Zendy

Samuel A. Shelburne | Zendy; Jorge Darcourt | Zendy; A. Clinton White | Zendy; Stephen B. Greenberg | Zendy; Richard J. Hamill | Zendy; Robert L. Atmar | Zendy; Fehmida Visnegarwala | Zendy

Open Access

The Role of Immune Reconstitution Inflammatory Syndrome in AIDS‐RelatedCryptococcus neoformansDisease in the Era of Highly Active Antiretroviral Therapy

Author(s) -

Samuel A. Shelburne,

Jorge Darcourt,

A. Clinton White,

Stephen B. Greenberg,

Richard J. Hamill,

Robert L. Atmar,

Fehmida Visnegarwala

Publication year - 2005

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/428618

Subject(s) - immune reconstitution inflammatory syndrome , cryptococcus neoformans , medicine , immunology , cryptococcosis , immune system , antiretroviral therapy , meningitis , cryptococcus , white blood cell , aids related opportunistic infections , disease , human immunodeficiency virus (hiv) , virology , viral disease , sida , microbiology and biotechnology , viral load , biology , psychiatry

This study of human immunodeficiency virus (HIV)-infected patients coinfected with Cryptococcus neoformans found that 30% of patients who initiated highly active antiretroviral therapy developed immune reconstitution inflammatory syndrome (IRIS). Patients with C. neoformans-related IRIS had higher cerebrospinal fluid opening pressures, glucose levels, and white blood cell counts, compared with patients with typical HIV-associated C. neoformans meningitis.

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