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This study of human immunodeficiency virus (HIV)-infected patients coinfected with Cryptococcus neoformans found that 30% of patients who initiated highly active antiretroviral therapy developed immune reconstitution inflammatory syndrome (IRIS). Patients with C. neoformans-related IRIS had higher cerebrospinal fluid opening pressures, glucose levels, and white blood cell counts, compared with patients with typical HIV-associated C. neoformans meningitis.

clinical infectious diseases/clinical infectious diseases (online. university of chicago. press)

The Role of Immune Reconstitution Inflammatory Syndrome in AIDS‐Related<i>Cryptococcus neoformans</i>Disease in the Era of Highly Active Antiretroviral Therapy

The Role of Immune Reconstitution Inflammatory Syndrome in AIDS‐RelatedCryptococcus neoformansDisease in the Era of Highly Active Antiretroviral Therapy