Genetic Analysis of Meningococci Carried by Children and Young Adults
Author(s) -
Heike Claus,
Martin Maiden,
Daniel J. Wilson,
Noel McCarthy,
Keith A. Jolley,
Rachel Urwin,
Frank Hessler,
Matthias Frosch,
Ulrich Vogel
Publication year - 2005
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/428590
Subject(s) - neisseria meningitidis , carriage , multilocus sequence typing , meningococcal disease , genotype , population , biology , microbiology and biotechnology , meningococcal vaccine , typing , virulence , genetic variation , virology , medicine , genetics , gene , bacteria , environmental health , pathology
Neisseria meningitidis is a diverse commensal bacterium that occasionally causes severe invasive disease. The relationship between meningococcal genotype and capsular polysaccharide, the principal virulence factor and vaccine component, was investigated in carried meningococci isolated from 8000 children and young adults in Bavaria, Germany.
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