Zinc Inhibits Cholera Toxin–Induced, but NotEscherichia coliHeat‐Stable Enterotoxin–Induced, Ion Secretion in Human Enterocytes | Zendy

Roberto Berni Canani | Zendy; Pia Cirillo | Zendy; Vittoria Buccigrossi | Zendy; Serena Ruotolo | Zendy; Annalisa Passariello | Zendy; Patrick De Luca | Zendy; Francesco Porcaro | Zendy; G. De Marco | Zendy; Alfredo Guarino | Zendy

Open Access

Zinc Inhibits Cholera Toxin–Induced, but NotEscherichia coliHeat‐Stable Enterotoxin–Induced, Ion Secretion in Human Enterocytes

Author(s) -

Roberto Berni Canani,

Pia Cirillo,

Vittoria Buccigrossi,

Serena Ruotolo,

Annalisa Passariello,

Patrick De Luca,

Francesco Porcaro,

G. De Marco,

Alfredo Guarino

Publication year - 2005

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/428504

Subject(s) - enterotoxin , cholera toxin , escherichia coli , heat stable enterotoxin , secretion , microbiology and biotechnology , toxin , escherichia coli proteins , zinc , cholera , chemistry , heat labile enterotoxin , microbial toxins , enterobacteriaceae , biology , biochemistry , organic chemistry , gene

Because zinc deficiency in malnourished children is associated with severe diarrhea, use of zinc supplementation has been proposed as an adjunct to oral rehydration. However, the effects of zinc on enterocyte ion transport are largely unknown. The objective of the present study was to investigate the effects of zinc on transepithelial ion transport under basal conditions and under conditions of enterotoxin-induced ion secretion.

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