Correlation between Immunologic Responses to a Recombinant Glycoprotein 120 Vaccine and Incidence of HIV‐1 Infection in a Phase 3 HIV‐1 Preventive Vaccine Trial
Author(s) -
Peter B. Gilbert,
Michael Peterson,
Dean Follmann,
Michael G. Hudgens,
Donald P. Francis,
Marc Gurwith,
William L. Heyward,
David V. Jobes,
Vladimir Popovic,
Steven G. Self,
Faruk Sinangil,
Donald S. Burke,
Phillip W. Berman
Publication year - 2005
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/428405
Subject(s) - immunology , vaccine trial , incidence (geometry) , antibody , hiv vaccine , medicine , cohort , virology , lentivirus , placebo , pre exposure prophylaxis , antibody titer , immune system , relative risk , titer , viral disease , confidence interval , human immunodeficiency virus (hiv) , men who have sex with men , physics , optics , alternative medicine , syphilis , pathology
An objective of the first efficacy trial of a candidate vaccine containing recombinant human immunodeficiency virus (HIV) type 1 envelope glycoprotein 120 (rgp120) antigens was to assess correlations between antibody responses to rgp120 and the incidence of HIV-1 infection.
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