Epidemiology of Invasive Haemophilus influenzae Type A Disease among Navajo and White Mountain Apache Children, 1988-2003
Author(s) -
Eugene V. Millar,
Katherine L. O’Brien,
James Watt,
Jairam R. Lingappa,
Ravi Pallipamu,
Nancy E. Rosenstein,
Danyang Hu,
Raymond Reid,
Mathuram Santosham
Publication year - 2005
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/428047
Subject(s) - medicine , population , incidence (geometry) , epidemiology , navajo , haemophilus influenzae , disease , vaccination , pediatrics , immunology , environmental health , microbiology and biotechnology , biology , linguistics , philosophy , physics , optics , antibiotics
Before the introduction of Haemophilus influenzae type b (Hib) conjugate vaccines, rates of H. influenzae disease among Navajo and White Mountain Apache (WMA) children were among the highest reported worldwide. Routine Hib vaccination has significantly reduced rates of Hib disease in these populations. As Hib disease rates decrease to very low levels, there are concerns that non-type b strains of H. influenzae may emerge as more prevalent causes of invasive disease in children.
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