Serotype Distribution of Invasive Group B Streptococcal Isolates in Infants: Results from a Nationwide Active Laboratory Surveillance Study over 2 Years in Germany | Zendy

Kirsten Fluegge | Zendy; Sven Supper | Zendy; Anette Siedler | Zendy; Reinhard Berner | Zendy

Open Access

Serotype Distribution of Invasive Group B Streptococcal Isolates in Infants: Results from a Nationwide Active Laboratory Surveillance Study over 2 Years in Germany

Author(s) -

Kirsten Fluegge,

Sven Supper,

Anette Siedler,

Reinhard Berner

Publication year - 2005

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/427942

Subject(s) - serotype , meningitis , medicine , group b , virology , streptococcus agalactiae , group a , isolation (microbiology) , microbiology and biotechnology , streptococcus , biology , pediatrics , bacteria , genetics

We report the serotype distribution of invasive group B streptococci (GBS) isolated from 296 infants in Germany. Serotype distribution was as follows: serotype Ia, 15%; Ib, 5%; II, 5%; III, 65%; IV, 1%; and V, 8%. Analysis of serotype according to the source of isolation highlighted the considerable role of serotype III in meningitis in early-onset infection (82%) and late-onset infection (84%). Use of a trivalent GBS vaccine in Germany could theoretically provide protection against 84% and 94% of invasive early-onset and late-onset infections, respectively.

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