Occult Hepatitis B Virus Infection in HIV-Infected Patients with Isolated Antibodies to Hepatitis B Core Antigen: Aquitaine Cohort, 2002-2003
Author(s) -
D. Neau,
María Winnock,
AnneChristine Jouvencel,
Muriel Faure,
Laurent Castéra,
E. Legrand,
D. Lacoste,
J. M. Ragnaud,
M. Dupon,
H. Fleury,
MarieEdith Lafon,
François Dabis
Publication year - 2005
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/427882
Subject(s) - medicine , hepatitis b virus , virology , occult , antibody , antigen , virus , hepatitis b , viral disease , immunology , hepatitis , pathology , alternative medicine
We prospectively assessed the prevalence of occult hepatitis B virus (HBV) infection by investigating HBV replication in 160 human immunodeficiency virus (HIV)-infected patients with isolated antibodies to hepatitis B core antigen. This prevalence was 0.6% (1 case/160 patients; 95% confidence interval, 0%-3.4%). A second serum sample was collected later from 52 of the patients. HBV DNA was once again undetectable in all patients, except for the sole patient who had previously been found to be HBV DNA positive.
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