Prognostic Significance of JC Virus DNA Levels in Cerebrospinal Fluid of Patients with HIV-Associated Progressive Multifocal Leukoencephalopathy
Author(s) -
Simona Bossolasco,
Giorgio Maria Calori,
Francesca Moretti,
Antonio Boschini,
Davide Bertelli,
Maurizio Mena,
Simonetta Gerevini,
A. Bestetti,
Rosa Pedale,
Simone Sala,
Adriano Lazzarin,
Paola Cinque
Publication year - 2005
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/427698
Subject(s) - progressive multifocal leukoencephalopathy , medicine , jc virus , leukoencephalopathy , cerebrospinal fluid , viral disease , human immunodeficiency virus (hiv) , complication , opportunistic infection , slow virus , virus , antiretroviral therapy , aids related opportunistic infections , virology , immunopathology , central nervous system disease , immunology , sida , pathology , viral load , disease
Progressive multifocal leukoencephalopathy (PML) remains a frequent and life-threatening complication of human immunodeficiency virus (HIV) infection in the era of highly active antiretroviral therapy (HAART). Although one-half of patients with this disease will survive, the outcome is unpredictable at diagnosis, and prognostic markers are needed.
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