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Female‐to‐Male Infectivity of HIV‐1 among Circumcised and Uncircumcised Kenyan Men
Author(s) -
Jared M. Baeten,
Barbra A. Richardson,
Ludo Lavreys,
Joel P. Rakwar,
Kishorchandra Mandaliya,
Job J. Bwayo,
Joan K. Kreiss
Publication year - 2005
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/427656
Subject(s) - demography , infectivity , medicine , population , context (archaeology) , kenya , confidence interval , transmission (telecommunications) , confounding , cohort , gynecology , immunology , biology , environmental health , virus , paleontology , ecology , sociology , electrical engineering , engineering
A lack of male circumcision has been associated with increased risk of human immunodeficiency virus type 1 (HIV-1) acquisition in a number of studies, but questions remain as to whether confounding by behavioral practices explains these results. The objective of the present study was to model per-sex act probabilities of female-to-male HIV-1 transmission (i.e., infectivity) for circumcised and uncircumcised men, by use of detailed accounts of sexual behavior in a population with multiple partnerships.

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