Open AccessOmega‐3 Polyunsaturated Fatty Acids Impair In Vivo Interferon‐γ Responsiveness via Diminished Receptor Signaling
Author(s) -
Robert Irons,
Kevin L. Fritsche
Publication year - 2005
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/427264
Subject(s) - polyunsaturated fatty acid , biology , fish oil , immune system , cytokine , endocrinology , medicine , in vivo , immunology , fatty acid , biochemistry , microbiology and biotechnology , fishery , fish <actinopterygii>
A high intake of omega-3 polyunsaturated fatty acids (n-3 PUFAs) in mice causes impaired host resistance to Listeria monocytogenes. We wished to determine the role of interferon (IFN)-gamma signaling in this increased disease susceptibility.
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