Development and Characterization of a Severe Acute Respiratory Syndrome–Associated Coronavirus–Neutralizing Human Monoclonal Antibody That Provides Effective Immunoprophylaxis in Mice | Zendy

Thomas C. Greenough | Zendy; Gregory J. Babcock | Zendy; Anjeanette Roberts | Zendy; Héctor J. Hernández | Zendy; William D. Thomas | Zendy; Jennifer A. Coccia | Zendy; Robert F. Graziano | Zendy; M. S. Srinivasan | Zendy; Israel Lowy | Zendy; Robert W. Finberg | Zendy; Kanta Subbarao | Zendy; Leatrice Vogel | Zendy; Mohan Somasundaran | Zendy; Katherine Luzuriaga | Zendy; John L. Sullivan | Zendy; Donna M. Ambrosino | Zendy

Open Access

Development and Characterization of a Severe Acute Respiratory Syndrome–Associated Coronavirus–Neutralizing Human Monoclonal Antibody That Provides Effective Immunoprophylaxis in Mice

Author(s) -

Thomas C. Greenough,

Gregory J. Babcock,

Anjeanette Roberts,

Héctor J. Hernández,

William D. Thomas,

Jennifer A. Coccia,

Robert F. Graziano,

M. S. Srinivasan,

Israel Lowy,

Robert W. Finberg,

Kanta Subbarao,

Leatrice Vogel,

Mohan Somasundaran,

Katherine Luzuriaga,

John L. Sullivan,

Donna M. Ambrosino

Publication year - 2005

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/427242

Subject(s) - epitope , monoclonal antibody , virology , antibody , coronavirus , glycoprotein , vero cell , ectodomain , biology , epitope mapping , neutralizing antibody , microbiology and biotechnology , virus , immunology , receptor , medicine , covid-19 , biochemistry , disease , pathology , infectious disease (medical specialty)

Severe acute respiratory syndrome (SARS) remains a significant public health concern after the epidemic in 2003. Human monoclonal antibodies (MAbs) that neutralize SARS-associated coronavirus (SARS-CoV) could provide protection for exposed individuals.

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