Immune and Functional Role of Nitric Oxide in a Mouse Model of Respiratory Syncytial Virus Infection
Author(s) -
James M. Stark,
Amir Khan,
Constance Chiappetta,
Hasen Xue,
Joseph L. Alcorn,
Giuseppe N. Colasurdo
Publication year - 2005
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/427241
Subject(s) - bronchoalveolar lavage , nitric oxide synthase , immunology , lung , respiratory system , nitric oxide , virus , interferon , immune system , cytokine , interferon gamma , medicine , biology
Respiratory syncytial virus (RSV) infection of respiratory epithelial cell cultures increases expression of inducible nitric oxide synthase (iNOS). The present study was designed to evaluate both the effect of RSV infection on expression of iNOS and the role of NO in the host responses to RSV infection in vivo.
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