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Familial Aggregation of Cerebral Malaria and Severe Malarial Anemia
Author(s) -
Stéphane Ranque,
Innocent Safeukui,
Belco Poudiougou,
Abdoulaye Traoré,
Modibo Keita,
Diamori Traoré,
Mahamadou Diakité,
Mahamadou B. Cissé,
Marouf M. Keita,
Ogobara K. Doumbo,
Alain Dessein
Publication year - 2005
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/427238
Subject(s) - odds ratio , malaria , sibling , odds , confidence interval , medicine , family history , anemia , sma* , pediatrics , demography , logistic regression , immunology , psychology , developmental psychology , mathematics , combinatorics , sociology
The predominant manifestations of severe malaria in African children are cerebral malaria (CM) and severe malarial anemia (SMA). As a first step toward a family-based approach to identify the environmental and genetic pathways that contribute to severe malaria, we tested whether it aggregates within families.

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