Prevalence of Antiretroviral Drug Resistance Mutations in Chronically HIV-Infected, Treatment-Naive Patients: Implications for Routine Resistance Screening before Initiation of Antiretroviral Therapy
Author(s) -
Richard M. Novak,
L. Chen,
Rodger D. MacArthur,
John D. Baxter,
Katherine Huppler Hullsiek,
Grace Peng,
Ying Xiang,
Christopher Henely,
Barry Schmetter,
J. Uy,
Mary van den Berg-Wolf,
Michael J. Kozal
Publication year - 2005
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/427212
Subject(s) - medicine , drug resistance , resistance mutation , hiv drug resistance , confidence interval , reverse transcriptase , virology , logistic regression , drug naïve , reverse transcriptase inhibitor , immunology , viral load , sida , viral disease , virus , drug , antiretroviral therapy , polymerase chain reaction , gene , pharmacology , biology , genetics
The prevalence of drug resistance among persons with newly acquired human immunodeficiency virus (HIV) infection is well documented. However, it is unclear to what extent these mutations persist in chronically infected, treatment-naive patients.
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