The Molecular Epidemiology of Streptococcus pneumoniae with Quinolone Resistance Mutations
Author(s) -
Sandra S. Richter,
Kristopher P. Heilmann,
Susan E. Beekmann,
N. J. Miller,
C. Rice,
G V Doern
Publication year - 2004
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/426817
Subject(s) - pulsed field gel electrophoresis , levofloxacin , microbiology and biotechnology , quinolone , streptococcus pneumoniae , ciprofloxacin , molecular epidemiology , biology , minimum inhibitory concentration , medicine , virology , genotype , genetics , antibiotics , gene
The purpose of this study was to determine the prevalence of fluoroquinolone resistance and quinolone resistance-determining region (QRDR) mutations among Streptococcus pneumoniae isolates in the United States during the period of 2001-2002. A second objective was to examine the genetic relatedness of pneumococcal isolates with parC and/or gyrA mutations during the period of 1994-2002.
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