Corticoids Normalize Leukocyte Production of Macrophage Migration Inhibitory Factor in Septic Shock | Zendy

Virginie Maxime | Zendy; Catherine Fitting | Zendy; Djillali Annane | Zendy; JeanMarc Cavaillon | Zendy

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Corticoids Normalize Leukocyte Production of Macrophage Migration Inhibitory Factor in Septic Shock

Author(s) -

Virginie Maxime,

Catherine Fitting,

Djillali Annane,

JeanMarc Cavaillon

Publication year - 2004

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/426401

Subject(s) - macrophage migration inhibitory factor , septic shock , peripheral blood mononuclear cell , ex vivo , glucocorticoid , lipopolysaccharide , immunology , cytokine , proinflammatory cytokine , sepsis , medicine , shock (circulatory) , in vivo , endocrinology , biology , inflammation , in vitro , biochemistry , microbiology and biotechnology

A regulatory loop between macrophage migration inhibitory factor (MIF) and glucocorticoids has been characterized in animal models. Renewed interest in glucocorticoid treatment for septic shock offers an opportunity to analyze this regulatory loop in humans.

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