Hemochromatosis Mutations in Iranians with Hepatitis B Virus Infection
Author(s) -
Hossein Sendi,
Tahereh Ghaziani,
Mohammad Reza Zali,
Peyman Adibi,
Mahvash Agah,
Maryam Jazayeri,
Saeid Shahraz,
Lars O. Magnius,
Herbert L. Bonkovsky
Publication year - 2005
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/426143
Subject(s) - medicine , hemochromatosis , exact test , virology , virus , viral disease , mutation , hepatitis b virus , hepatitis b , hereditary hemochromatosis , gene , gastroenterology , genetics , biology
In this study, the frequencies of the common hemochromatosis gene mutations were assessed in 75 Iranian subjects with chronic hepatitis B infection. We found that the major C282Y mutation was significantly more frequent in subjects infected with hepatitis B virus (4%) than in 194 control subjects (0%, P=.02; Fisher's exact test).
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