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Two Cases of Fatal Shock after Transfusion of Platelets Contaminated by Staphylococcus aureus: Role of Superantigenic Toxins
Author(s) -
T. Perpoint,
Gérard Lina,
Claire Poyart,
Bertille de Barbeyrac,
R Traineau,
Michel Jeanne,
François Vandenesch,
Jérôme Etienne
Publication year - 2004
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/425499
Subject(s) - staphylococcus aureus , medicine , toxic shock syndrome , shock (circulatory) , platelet , microbiology and biotechnology , septic shock , staphylococcal infections , micrococcaceae , staphylococcus , sepsis , immunology , bacteria , biology , genetics
We detected Staphylococcus aureus superantigenic toxins in the platelet infusion bags that had been used for 2 patients who subsequently developed transfusion-associated Staphylococcus aureus infection. Both patients, who were immunodeficient, developed manifestations of toxic shock syndrome and septic shock, and they died soon after the onset of infection.

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