Open AccessSimian Parvovirus Infection: A Potential Zoonosis
Author(s) -
Kevin Brown,
Zhengwen Liu,
Giorgio Gallinella,
Susan Wong,
Ian P. Mills,
M. Gerard O’Sullivan
Publication year - 2004
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/425420
Subject(s) - peripheral blood mononuclear cell , virology , biology , bone marrow , parvovirus , macaque , parvoviridae , immunology , antibody , virus , in vitro , paleontology , biochemistry
Simian parvovirus (SPV) causes severe anemia in immunocompromised macaques. The closely related erythrovirus, parvovirus B19, causes anemia in susceptible humans and can be grown in human bone marrow mononuclear cells in vitro. We hypothesized that SPV may infect humans and replicate in human bone marrow mononuclear cells.
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