Inhalation of Nitric Oxide in the Treatment of Severe Acute Respiratory Syndrome: A Rescue Trial in Beijing | Zendy

L. Chen | Zendy; P. Liu | Zendy; Hu Gao | Zendy; Bin Sun | Zendy; Daniel L. Chao | Zendy; Fahui Wang | Zendy; Yuanyuan Zhu | Zendy; Göran Hedenstierna | Zendy; C. G. Wang | Zendy

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Inhalation of Nitric Oxide in the Treatment of Severe Acute Respiratory Syndrome: A Rescue Trial in Beijing

Author(s) -

L. Chen,

P. Liu,

Hu Gao,

Bin Sun,

Daniel L. Chao,

Fahui Wang,

Yuanyuan Zhu,

Göran Hedenstierna,

C. G. Wang

Publication year - 2004

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/425357

Subject(s) - medicine , nitric oxide , inhalation , anesthesia , respiratory system , airway , oxygenation

Inhalation of nitric oxide (NO) improved arterial oxygenation and enabled the reduction of inspired oxygen therapy and airway pressure support in patients with severe acute respiratory syndrome (SARS). In addition, chest radiography showed decreased spread or density of lung infiltrates, and the physiological effects remained after termination of inhaled NO therapy. These findings suggest not only a pulmonary vasodilator effect of inhaled NO, but also an effect on SARS.

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