Trends in AIDS-Defining and Non--AIDS-Defining Malignancies among HIV-Infected Patients: 1989-2002 | Zendy

Roger Bedimo | Zendy; Ray Y. Chen | Zendy; Neil A. Accortt | Zendy; James L. Raper | Zendy; Charles E. Linn | Zendy; Jeroan J. Allison | Zendy; J W Dubay | Zendy; M. S. Saag | Zendy; Craig Hoesley | Zendy

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Trends in AIDS-Defining and Non--AIDS-Defining Malignancies among HIV-Infected Patients: 1989-2002

Author(s) -

Roger Bedimo,

Ray Y. Chen,

Neil A. Accortt,

James L. Raper,

Charles E. Linn,

Jeroan J. Allison,

J W Dubay,

M. S. Saag,

Craig Hoesley

Publication year - 2004

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/424883

Subject(s) - medicine , incidence (geometry) , human immunodeficiency virus (hiv) , aids related complex , antiretroviral therapy , sida , viral disease , immunology , viral load , physics , optics

In a comparison of rates of acquired immunodeficiency syndrome (AIDS)-defining malignancies (ADMs) for 1989-1996 versus 1997-2002, we found a decrease in ADMs (rate ratio, 0.31; P<.0001) and a significant increase in non-AIDS-defining malignancies (non-ADMs; rate ratio, 10.87; P<.0002). The mean CD4 cell count was lower among patients with ADMs than among those with non-ADMs. A longer duration of survival during highly active antiretroviral therapy might explain the increasing incidence of non-ADMs.

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