Valacyclovir and Acyclovir for Suppression of Shedding of Herpes Simplex Virus in the Genital Tract | Zendy

Rachna Gupta | Zendy; Anna Wald | Zendy; Elizabeth M. Krantz | Zendy; Stacy Selke | Zendy; Terri Warren | Zendy; Mauricio VargasCortes | Zendy; Gerri B. Miller | Zendy; Lawrence Corey | Zendy

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Valacyclovir and Acyclovir for Suppression of Shedding of Herpes Simplex Virus in the Genital Tract

Author(s) -

Rachna Gupta,

Anna Wald,

Elizabeth M. Krantz,

Stacy Selke,

Terri Warren,

Mauricio VargasCortes,

Gerri B. Miller,

Lawrence Corey

Publication year - 2004

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/424519

Subject(s) - viral shedding , herpes simplex virus , placebo , valaciclovir , virology , medicine , subclinical infection , herpes genitalis , herpesviridae , aciclovir , virus , genital herpes , immunology , viral disease , pathology , alternative medicine

Valacyclovir exhibits better oral absorption and higher, more prolonged serum concentrations than oral acyclovir. The efficacy of valacyclovir and acyclovir on genital herpes simplex virus (HSV) shedding was assessed in a double-blind, 3-period crossover trial.

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