Early‐Onset Guillain‐Barré Syndrome Associated with Reactivation of Epstein‐Barr Virus Infection after Nonmyeloablative Stem Cell Transplantation
Author(s) -
Menachem Bitan,
Reuven Or,
Michael Y. Shapira,
Nurith Mador,
Igor Resnick,
Niveen Saleh,
Klaus M. Weinberger,
Simcha Samuel,
Esther M. Schechter,
Shimon Slavin,
Dana G. Wolf
Publication year - 2004
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/424015
Subject(s) - medicine , epstein–barr virus , guillain barre syndrome , virus , transplantation , immunology , virology , disease , epstein–barr virus infection , viral disease , stem cell , herpesviridae , pathology , biology , genetics
We report a case of early-onset acute Guillain-Barre syndrome associated with reactivation of Epstein-Barr virus (EBV) infection after nonmyeloablative stem cell transplantation (NST). Reactivation of EBV infection preceded disease onset, and the virus load increased concomitantly with disease progression (doubling time, 2.7 days). This case raises concern about the expanding scope of manifestations associated with reactivation of EBV infection after NST.
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