Prevalence of Dihydropteroate Synthase Mutants in HIV‐Infected South African Children withPneumocystis jiroveciPneumonia | Zendy

Heather J. Zar | Zendy; Míriam J. Álvarez-Martínez | Zendy; Amy L. Harrison | Zendy; Steve Meshnick | Zendy

Open Access

Prevalence of Dihydropteroate Synthase Mutants in HIV‐Infected South African Children withPneumocystis jiroveciPneumonia

Author(s) -

Heather J. Zar,

Míriam J. Álvarez-Martínez,

Amy L. Harrison,

Steve Meshnick

Publication year - 2004

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/424010

Subject(s) - dhps , dihydropteroate synthase , virology , population , pneumocystis pneumonia , pneumocystis jirovecii , biology , medicine , microbiology and biotechnology , immunology , pyrimethamine , human immunodeficiency virus (hiv) , malaria , chloroquine , plasmodium falciparum , environmental health

Pneumocystis jiroveci (formerly Pneumocystis carinii) pneumonia (PCP) is a major cause of mortality in human immunodeficiency virus (HIV)-infected infants in Africa, but the prevalence of mutations in the gene encoding dihydropteroate synthase (DHPS) in isolates from Africa has not been reported.

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