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Differences in Survival, Brain Damage, and Cerebrospinal Fluid Cytokine Kinetics Due to Meningitis Caused by 3 DifferentStreptococcus pneumoniaeSerotypes: Evaluation in Humans and in 2 Experimental Models
Author(s) -
Christian Østergaard,
Christian Brandt,
Helle Bossen Konradsen,
S Samuelsson
Publication year - 2004
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/423852
Subject(s) - streptococcus pneumoniae , meningitis , serotype , cerebrospinal fluid , case fatality rate , medicine , immunology , brain abscess , biology , abscess , microbiology and biotechnology , antibiotics , surgery , epidemiology
Experimental meningitis with Streptococcus pneumoniae serotypes 1, 3, and 9 has resulted in pronounced differences in disease severity, but clinical meningitis studies addressing serotype-related differences in case-fatality rates are lacking.

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