Intrathecal Production and Secretion of Vascular Endothelial Growth Factor during Cryptococcal Meningitis | Zendy

Frank E. J. Coenjaerts | Zendy; Michiel van der Flier | Zendy; Pauline N. M. Mwinzi | Zendy; Annemarie E. Brouwer | Zendy; Jelle Scharringa | Zendy; Wendy Chaka | Zendy; Marieke Aarts | Zendy; Adul Rajanuwong | Zendy; David van de Vijver | Zendy; Thomas S. Harrison | Zendy; Andy I. M. Hoepelman | Zendy

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Intrathecal Production and Secretion of Vascular Endothelial Growth Factor during Cryptococcal Meningitis

Author(s) -

Frank E. J. Coenjaerts,

Michiel van der Flier,

Pauline N. M. Mwinzi,

Annemarie E. Brouwer,

Jelle Scharringa,

Wendy Chaka,

Marieke Aarts,

Adul Rajanuwong,

David van de Vijver,

Thomas S. Harrison,

Andy I. M. Hoepelman

Publication year - 2004

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/423849

Subject(s) - cryptococcal meningitis , vascular endothelial growth factor , intrathecal , meningitis , intracranial pressure , medicine , immunology , pathology , vegf receptors , anesthesia , surgery , human immunodeficiency virus (hiv) , viral disease

Patients with cryptococcal meningitis (CM) show elevated intracranial pressure (ICP) and blood-brain barrier (BBB) disruption in most cases. Elevated ICP is an important contributor to mortality. Vascular endothelial growth factor (VEGF) might be the mediator of BBB disruption during CM.

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