Detection of Antigen in Bronchial Epithelium and Macrophages in Acute Kawasaki Disease by Use of Synthetic Antibody
Author(s) -
Anne H. Rowley,
Susan C. Baker,
Stanford T. Shulman,
Francesca L. Garcia,
Judith A. GuzmanCottrill,
Pauline M. Chou,
Masaru Terai,
Tomisaku Kawasaki,
Mitra B. Kalelkar,
Susan E. Crawford
Publication year - 2004
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/422648
Subject(s) - antigen , antibody , pathogenesis , kawasaki disease , immunology , pathology , medicine , immunohistochemistry , artery
Kawasaki disease (KD) is the most common acquired cardiac disease in children in developed nations. The etiology is unknown, but a ubiquitous infectious agent appears to be likely. Immunoglobulin A plasma cells infiltrate inflamed tissues in acute KD, producing oligoclonal, antigen-driven antibodies.
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