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Impact of Indinavir on the Quality of Life in Patients with Advanced HIV Infection Treated with Zidovudine and Lamivudine
Author(s) -
Paul Coplan,
J.R. Cook,
George W. Carides,
Joseph F. Heyse,
Albert W. Wu,
Scott M. Hammer,
Bach Nguyen,
Anne R. Meibohm,
Mark J. DiNubile
Publication year - 2004
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/422520
Subject(s) - indinavir , zidovudine , lamivudine , medicine , stavudine , reverse transcriptase inhibitor , quality of life (healthcare) , visual analogue scale , immunology , oncology , viral load , surgery , viral disease , human immunodeficiency virus (hiv) , virus , antiretroviral therapy , hepatitis b virus , nursing
In AIDS Clinical Trial Group (ACTG) study 320, triple-combination antiretroviral therapy including indinavir significantly slowed progression to acquired immunodeficiency syndrome or death, compared with treatment with dual nucleoside reverse-transcriptase inhibitors (NRTIs) alone, in zidovudine-experienced patients with advanced human immunodeficiency virus (HIV) infection. We examined the impact of indinavir on quality of life in participants from this study.

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