Concurrent Cerebral American Trypanosomiasis and Toxoplasmosis in a Patient with AIDS | Zendy

Tae-Kyung Yoo | Zendy; Anton Mlikotic | Zendy; Marcia E. Cornford | Zendy; C. K. Beck | Zendy

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Concurrent Cerebral American Trypanosomiasis and Toxoplasmosis in a Patient with AIDS

Author(s) -

Tae-Kyung Yoo,

Anton Mlikotic,

Marcia E. Cornford,

C. K. Beck

Publication year - 2004

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/422456

Subject(s) - medicine , trypanosoma cruzi , toxoplasmosis , toxoplasma gondii , differential diagnosis , trypanosomiasis , chagas disease , cerebrospinal fluid , nifurtimox , magnetic resonance imaging , pediatrics , immunology , pathology , radiology , parasite hosting , antibody , world wide web , computer science

We report a case of concurrent cerebral infection with Trypanosoma cruzi and Toxoplasma gondii in a patient with acquired immunodeficiency syndrome (AIDS). A 22-year-old El Salvadoran man initially improved during receipt of antitoxoplasmosis therapy, but he had rapidly progressive hemiplegia. Magnetic resonance imaging showed an abnormal finding in the left internal capsule, and cytological analysis of cerebrospinal fluid revealed T. cruzi trypomastigotes. Despite prompt therapy with nifurtimox, the patient's mental status declined, and he died of nosocomial complications. Although infrequent, T. cruzi infection should be considered in the differential diagnosis of brain lesions in patients with AIDS from regions of endemicity.

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