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Increased Adhesion Molecule and Chemokine Receptor Expression on CD8+T Cells Trafficking to Cerebrospinal Fluid in HIV‐1 Infection
Author(s) -
Barbara L. Shacklett,
Catherine A. Cox,
David T. Wilkens,
Robert Karlsson,
Annelie Nilsson,
Douglas F. Nixon,
Richard W. Price
Publication year - 2004
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/421244
Subject(s) - cxcr3 , cxcl10 , cd8 , chemokine , biology , lymphocyte function associated antigen 1 , cxcl16 , ccl5 , chemokine receptor ccr5 , cytotoxic t cell , cell adhesion molecule , immunology , leukocyte trafficking , chemokine receptor , t cell , antigen , immune system , intercellular adhesion molecule 1 , il 2 receptor , in vitro , biochemistry
The central nervous system (CNS) is a recognized target for human immunodeficiency virus type 1 (HIV-1). CD8(+) T cells may mediate viral clearance from the CNS but also may contribute to immune-mediated neuronal damage.

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