Unintended Smallpox Vaccination of HIV-1--Infected Individuals in the United States Military | Zendy

Sybil Tasker | Zendy; Glenn Schnepf | Zendy; M. Lim | Zendy; H. E. Caraviello | Zendy; A. Armstrong | Zendy; Mary Bavaro | Zendy; Brian K. Agan | Zendy; Judith Delmar | Zendy; Naomi Aronson | Zendy; Mairi Wallace | Zendy; John D. Grabenstein | Zendy

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Unintended Smallpox Vaccination of HIV-1--Infected Individuals in the United States Military

Author(s) -

Sybil Tasker,

Glenn Schnepf,

M. Lim,

H. E. Caraviello,

A. Armstrong,

Mary Bavaro,

Brian K. Agan,

Judith Delmar,

Naomi Aronson,

Mairi Wallace,

John D. Grabenstein

Publication year - 2004

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/420938

Subject(s) - smallpox , medicine , virology , vaccination , human immunodeficiency virus (hiv) , smallpox vaccine , immunology , mass vaccination , viral disease , viral load , virus , biology , vaccinia , biochemistry , gene , recombinant dna

We identified 10 individuals who had undiagnosed human immunodeficiency virus type 1 (HIV-1) infection at the time of smallpox vaccination. Mean CD4 cell count was 483 cells/mm3 (range, 286-751 cells/mm3), and mean log10 plasma HIV-1 RNA load was 4.13 copies/cm3 (range, 2.54-5.16 copies/cm3). All vaccinees (3 primary and 7 repeat) had a normal, robust reaction without complications. Smallpox vaccine was well-tolerated in this small series of HIV-1-infected military personnel.

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