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Respiratory Syncytial Virus Induces Pneumonia, Cytokine Response, Airway Obstruction, and Chronic Inflammatory Infiltrates Associated with Long‐Term Airway Hyperresponsiveness in Mice
Author(s) -
Hasan S. Jafri,
Susana ChávezBueno,
Asunción Mejías,
Ana M. Gómez,
Ana María Ríos,
Shahryar S. Nassi,
Munira Yusuf,
Payal Kapur,
R. Doug Hardy,
Jeanine Hatfield,
Beverly Barton Rogers,
Karen Krisher,
Octavio Ramilo
Publication year - 2004
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/386372
Subject(s) - medicine , pneumonia , respiratory tract , immunology , respiratory system , airway obstruction , virus , respiratory disease , mononegavirales , cytokine , airway , lower respiratory tract infection , paramyxoviridae , respiratory tract infections , lung , viral disease , anesthesia
Respiratory syncytial virus (RSV) infection is associated with acute morbidity (e.g., pneumonia and airway obstruction [AO]) and long-term complications (e.g., airway hyperresponsiveness [AHR]). We present a comprehensive evaluation of the acute and chronic phases of RSV respiratory tract infection, using a mouse model.

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