High Resolution Anoscopy Findings for Men Who Have Sex with Men: Inaccuracy of Anal Cytology as a Predictor of Histologic High-Grade Anal Intraepithelial Neoplasia and the Impact of HIV Serostatus
Author(s) -
Lori Panther,
Katiri Wagner,
JoAnn Proper,
Dana Fugelso,
P A Chatis,
Will Weeden,
Imad Nasser,
John P. Doweiko,
Bruce J. Dezube
Publication year - 2004
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/383574
Subject(s) - serostatus , medicine , men who have sex with men , dysplasia , biopsy , papanicolaou stain , intraepithelial neoplasia , cytology , anus , gynecology , pathology , human immunodeficiency virus (hiv) , syphilis , surgery , viral load , virology , prostate , cancer , cervical cancer
We compared the pathological diagnoses obtained by anal Papanicolaou (Pap) smear with those obtained by anal biopsy or by surgical excision for 153 men who have sex with men (MSM). Analysis of these paired specimens showed that anal Pap smears were an inaccurate predictor of high-grade anal dysplasia, regardless of human immunodeficiency virus (HIV) serostatus. The presence of any abnormal anal cytological finding indicates a potential for high-grade dysplasia on histological examination of MSM.
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